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Procaine benzylpenicillin (rINN), also known as procaine penicillin, is an antibiotic useful for the treatment of a number of bacterial infections. It is a form of penicillin which is a combination of benzylpenicillin and the local anaesthetic agent procaine. Following deep intramuscular injection, it is slowly absorbed into the circulation and hydrolysed to benzylpenicillin — thus it is used where prolonged low concentrations of benzylpenicillin are required. This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin. It is widely used in veterinary settings. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. ==Uses== Specific indications for procaine penicillin include: *Syphilis * *In the United States, Bicillin C-R (a injectable suspension which 1.2 million units of benzathine penicillin and 1.2 million units of procaine penicillin per 4 ml) is not recommended for treating syphilis, since it contains only half the recommended dose of benzathine penicillin. Medication errors have been made due to the confusion between Bicillin L-A & Bicillin C-R. As a result, changes in product packaging have been made; specifically, the statement "Not for the Treatment of Syphilis" has been added in red text to both the Bicillin CR and Billin CR 900/300 syringe labels.〔United States Food & Drug Administration. ("FDA Strengthens Labels of Two Specific Types of Antibiotics to Ensure Proper Use." ) Published December 1, 2004. Last accessed June 18, 2007.〕 *Respiratory tract infections where compliance with oral treatment is unlikely *Alongside Pen V and Erythromycin, Bicillin C-R is used to treat strep throat, given as one IM injection *Cellulitis, erysipelas *Procaine penicillin is also used as an adjunct in the treatment of anthrax. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Procaine benzylpenicillin」の詳細全文を読む スポンサード リンク
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